Dr. Frankel's Journal

Archive for March, 2015

PATIENT WITH CROHN’S DISEASE SWITCHES FROM ORAL TO RECTAL CBD AND LOWERS DOSE

March 31, 2015
Allan Frankel, MD

I have been following a young male with relatively severe Crohn’s disease. He has been on an assorted group of meds without adequate control. He first presented to me nearly a year ago and has done very well on CBD…

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MORE EVIDENCE ON USEFULNESS OF RECTAL CBD

March 17, 2015
Allan Frankel, MD

6/14/2016: UPDATED INFORMATION AND MULTIPLE BLOGS I HAVE SINCE WRITTEN SHOW THAT WHOLE PLANT CANNABIS IS NOT RECTALLY ABSORBED. THC CAN BE RECTALLY ABSORBED BUT ONLY IF BONDED TO A SEPARATE MOLECULE, SUCH AS HEMI-SUCCINATE. MANY PATIENTS USE HIGH DOSES OF…

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WHOLE PLANT CANNABIS REQUIRES LOWER CANNABIDIOL DOSE

March 6, 2015
Allan Frankel, MD

I have spoken about the differences in therapeutic dosages of whole plant cannabis extracts versus laboratory synthesized molecular cannabinoids and highly purified cannabis extracts.  It is very clear from the large volume of anecdotal evidence that much lower dosing is…

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