REFERENCES

CANNABIS EFFECTIVENESS PEER REVIEWED STUDIES

For a great initial review of The Literature Go To http://norml.org/index.cfm?Group_ID=7002

http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01238.x/pdf

Legal Links

Educational Documents

Mar. 1, 2011
European Journal of Neurology

Aug. 30, 2010
Canadian Medical Association Journal

Nov. 6, 2009
Journal of Pain and Symptom Management

Aug. 2008
Neuropsychopharmacology
Vol. 34
Pages 672-680

June 2008
Journal of Pain
Vol. 9, Issue 6,
Pages 505-521

Mar. 2007
European Journal of Neurology
Vol. 14, No. 3,
Page 290

Feb. 13, 2007
Neurology
Vol. 68, Pages 515-521

Sep. 2005
Neurology
Vol. 65, Issue 6, Pages 812-819

Dec. 2004
Pain
Vol. 112, Issue 3, Pages 299-306

Aug. 2004
Multiple Sclerosis
Vol. 10, Issue 4, Pages 434-441

Aug. 2004
Multiple Sclerosis
Vol. 10, Issue 4, Pages 417-424

Feb. 2003
Clinical Rehabilitation
Vol. 17, Pages 18-26

Dec. 25, 2007
Journal of the National Cancer Institute
Vol. 100, Number 1, Page 51

Aug. 15, 2007
Journal of Acquired Immune Deficiency Syndromes
Vol. 45, Number 5, Pages 545-554

Feb. 2005
Journal of Neuroscience
Vol. 25 Issue 8, Pages 1904-1913

Sep. 2004
Movement Disorders
Vol. 19, Issue 9, Pages 1102-1106

Aug. 2004
Multiple Sclerosis
Vol. 10, Issue 4, Pages 425-433

Oct. 2003
Nature Reviews – Cancer
Vol. 3 Oct. 2003 pp. 745-755

Aug. 2003
Annals of Internal Medicine
Vol. 139, Issue 4, Pages 258-266

Mar. 2003
Pain
Vol. 102, Issue 1-2, Pages 211-216
Jan. 2002
Journal of Cannabis Therapeutics

Nov. 2001
International Journal of Drug Policy
Vol. 12, Issue 5-6, Pages 377-383

July 2001
Pharmacology, Biochemistry and Behavior
Vol. 69, Issue 3-4, Pages 343-350

Apr. 2001
Nature
Vol. 410, Issue 6830, Page 763

2001
Journal of Cannabis Therapeutics
Vol. 1, Issue 3/4, Pages 183-205

Dec. 1998
Acta Psychiatrica Scandinavica
Vol. 98, Issue 6, Pages 502-506

Apr. – June 1998
Journal of Psychoactive Drugs
Vol. 30, Issue 2, Pages 171-177

1997
European Neurology
Vol. 38, Issue 1, pages 44-48

July 1991
American Journal of Clinical Oncology
Vol. 9, Issue 7, Pages 1314-1319

Oct. 2005
Journal of Clinical Investigation
10.1172/JCI25509

May 2005
Nature Medicine
doi:10.1038/nm1255

Sep. 2004
Neuropharmacology
Vol. 47, Issue 3, p. 315-323

Jan. 2003
Journal of Clinical Investigation
111:43-50

Rubio M, Villain H, Docagne F, Roussel BD, Ramos JA, et al. (2011) Pharmacological Activation/Inhibition of the Cannabinoid System Affects Alcohol Withdrawal-Induced Neuronal Hypersensitivity to Excitotoxic Insults. PLoS ONE 6(8): e23690. doi:10.1371/journal.pone.0023690

FOLLOWING GROUP ARE REFERENCED FROM DR. ETHAN RUSSO:

Taming THC: potential
cannabis synergy and
phytocannabinoid-terpenoid
entourage effects
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Crippa JA, Zuardi AW, Hallak JE (2010). [Therapeutical use of the
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5: 17.

CBD and Cancer

http://www.ncbi.nlm.nih.gov/pubmed/20053780

http://www.ncbi.nlm.nih.gov/pubmed/16728591

http://www.ncbi.nlm.nih.gov/pubmed/21566064

http://www.ncbi.nlm.nih.gov/pubmed/18833429

Tumor Studies:

http://www.ncbi.nlm.nih.gov/pubmed/18035205

http://www.ncbi.nlm.nih.gov/pubmed/14617682

Clinical Trials:

http://clinicaltrials.gov/ct2/results?term=cannabidiol

http://www.cannabis-med.org/studies/ww_en_db_study_search.php

 

REFERENCES CITED BY GW PHARMACEUTICALS
Windholz et al., The Merck Index, Tenth Edition (1983) p. 241, abstract No. 1723.* .
Mechoulam et al., "A Total Synthesis of d1-.DELTA..sup.1 -Tetrahydrocannabinol, the Active Constituent of Hashish.sup.1," Journal of the American Chemical Society, 87:14:3273-3275 (1965). .
Mechoulam et al., "Chemical Basis of Hashish Activity," Science, 18:611-612 (1970). .
Ottersen et al., "The Crystal and Molecular Structure of Cannabidiol," Acta Chem. Scand. B 31, 9:807-812 (1977). .
Cunha et al., "Chronic Administration of Cannabidiol to Healthy Volunteers and Epileptic Patients.sup.1," Pharmacology, 21:175-185 (1980). .
Consroe et al., "Acute and Chronic Antiepileptic Drug Effects in Audiogenic Seizure-Susceptible Rats," Experimental Neurology, Academic Press Inc., 70:626-637 (1980). .
Turkanis et al., "Electrophysiologic Properties of the Cannabinoids," J. Clin. Pharmacol., 21:449S-463S (1981). .
Carlini et al., "Hypnotic and Antielpileptic Effects of Cannabidiol," J. Clin. Pharmacol., 21:417S-427S (1981). .
Karler et al., "The Cannabinoids as Potential Antiepileptics," J. Clin. Pharmacol., 21:437S-448S (1981). .
Consroe et al., "Antiepileptic Potential of Cannabidiol Analgos," J. Clin. Pharmacol., 21:428S-436S (1981). .
Colasanti et al., "Ocular Hypotension, Ocular Toxicity,a nd Neurotoxicity in Response to Marihuana Extract and Cannabidiol," Gen Pharm., Pergamon Press Ltd., 15(6):479-484 (1984). .
Colasanti et al., "Intraocular Pressure, Ocular Toxicity and Neurotoxicity after Administration of Cannabinol or Cannabigerol," Exp. Eye Res., Academic Press Inc., 39:251-259 (1984). .
Volfe et al., "Cannabinoids Block Release of Serotonin from Platelets Induced by Plasma frm Migraine Patients," Int. J. Clin. Pharm. Res., Bioscience Ediprint Inc., 4:243-246 (1985). .
Agurell et al., "Pharmacokinetics and Metabolism of .DELTA..sup.1 -Tetrahydrocannabinol and Other Cannabinoids with Emphasis on Man*," Pharmacological Reviews, 38(1):21-43 (1986). .
Karler et al., "Different Cannabinoids Exhibit Different Pharmacological and Toxicological Properties,"NIDA Res. Monogr., 79:96-107 (1987). .
Samara et al., "Pharmacokinetics of Cannabidiol in Dogs," Drug Metabolism and Disposition, 16(3):469-472 (1988). .
Choi, "Glutamate Neurotoxicity and Diseases of the Nervous System," Neuron, Cell Press, 1:623-634 (1988). .
Eshhar et al., "Neuroprotective and Antioxidant Activities of HU-211, A Novel NMDA Receptor Antagonist," European Journal of Pharmacology, 283:19-29 (1995). .
Skaper et al., "The ALIAmide Palmitoylethanolamide and Cannabinoids, but not Anandamide, are Protective in a Delayed Postglutamate Paradigm of Excitotoxic Death in Cerebellar Granule Neurons," Neurobiology, Proc. Natl. Acad. Sci. USA, 93:3984-3989 (1996). .
Alonso et al., "Simple Synthesis of 5-Substituted Resorcinols: A Revisited Family of Interesting Bioactive Molecules," J. Org. Chem., American Chemical Society, 62(2):417-421 (1997). .
Combes et al. "A Simple Synthesis of the Natural 2,5-Dialkylresorcinol Free Radical Scavenger Antioxidant: Resorstation," Synthetic Communications, Marcel Dekker, Inc., 27(21):3769-3778 (1997). .
Shohami et al., "Oxidative Stress in Closed-Head Injury: Brain Antioxidant Capacity as an Indicator of Functional Outcome," Journal of Cerebral Blood Flow and Metabolism, Lippincott-Raven Publishers, 17(10):1007-1019 (1997). .
Zurier et al., "Dimethylheptyl-THC-11 OIC Acid," Arthritis & Rheumatism, 41(1):163-170 (1998). .
Hampson et al., "Dual Effects of Anandamide on NMDA Receptor-Mediated Responses and Neurotransmission," Journal of Neurochemistry, Lippincott-Raven Publishers, 70(2):671-676 (1998). .
Hampson et al., "Cannabidiol and (-).DELTA..sup.9 -tetrahydrocannabiono are Neuroprotective Antioxidants," Medical Sciences, Proc. Natl. Acad. Sci. USA, 8268-8273 (1998)..
Windholz et al., The Merck Index, Tenth Edition (1983) p. 241, abstract No. 1723.* .
Mechoulam et al., "A Total Synthesis of d1-.DELTA..sup.1 -Tetrahydrocannabinol, the Active Constituent of Hashish.sup.1," Journal of the American Chemical Society, 87:14:3273-3275 (1965). .
Mechoulam et al., "Chemical Basis of Hashish Activity," Science, 18:611-612 (1970). .
Ottersen et al., "The Crystal and Molecular Structure of Cannabidiol," Acta Chem. Scand. B 31, 9:807-812 (1977). .
Cunha et al., "Chronic Administration of Cannabidiol to Healthy Volunteers and Epileptic Patients.sup.1," Pharmacology, 21:175-185 (1980). .
Consroe et al., "Acute and Chronic Antiepileptic Drug Effects in Audiogenic Seizure-Susceptible Rats," Experimental Neurology, Academic Press Inc., 70:626-637 (1980). .
Turkanis et al., "Electrophysiologic Properties of the Cannabinoids," J. Clin. Pharmacol., 21:449S-463S (1981). .
Carlini et al., "Hypnotic and Antielpileptic Effects of Cannabidiol," J. Clin. Pharmacol., 21:417S-427S (1981). .
Karler et al., "The Cannabinoids as Potential Antiepileptics," J. Clin. Pharmacol., 21:437S-448S (1981). .
Consroe et al., "Antiepileptic Potential of Cannabidiol Analgos," J. Clin. Pharmacol., 21:428S-436S (1981). .
Colasanti et al., "Ocular Hypotension, Ocular Toxicity,a nd Neurotoxicity in Response to Marihuana Extract and Cannabidiol," Gen Pharm., Pergamon Press Ltd., 15(6):479-484 (1984). .
Colasanti et al., "Intraocular Pressure, Ocular Toxicity and Neurotoxicity after Administration of Cannabinol or Cannabigerol," Exp. Eye Res., Academic Press Inc., 39:251-259 (1984). .
Volfe et al., "Cannabinoids Block Release of Serotonin from Platelets Induced by Plasma frm Migraine Patients," Int. J. Clin. Pharm. Res., Bioscience Ediprint Inc., 4:243-246 (1985). .
Agurell et al., "Pharmacokinetics and Metabolism of .DELTA..sup.1 -Tetrahydrocannabinol and Other Cannabinoids with Emphasis on Man*," Pharmacological Reviews, 38(1):21-43 (1986). .
Karler et al., "Different Cannabinoids Exhibit Different Pharmacological and Toxicological Properties,"NIDA Res. Monogr., 79:96-107 (1987). .
Samara et al., "Pharmacokinetics of Cannabidiol in Dogs," Drug Metabolism and Disposition, 16(3):469-472 (1988). .
Choi, "Glutamate Neurotoxicity and Diseases of the Nervous System," Neuron, Cell Press, 1:623-634 (1988). .
Eshhar et al., "Neuroprotective and Antioxidant Activities of HU-211, A Novel NMDA Receptor Antagonist," European Journal of Pharmacology, 283:19-29 (1995). .
Skaper et al., "The ALIAmide Palmitoylethanolamide and Cannabinoids, but not Anandamide, are Protective in a Delayed Postglutamate Paradigm of Excitotoxic Death in Cerebellar Granule Neurons," Neurobiology, Proc. Natl. Acad. Sci. USA, 93:3984-3989 (1996). .
Alonso et al., "Simple Synthesis of 5-Substituted Resorcinols: A Revisited Family of Interesting Bioactive Molecules," J. Org. Chem., American Chemical Society, 62(2):417-421 (1997). .
Combes et al. "A Simple Synthesis of the Natural 2,5-Dialkylresorcinol Free Radical Scavenger Antioxidant: Resorstation," Synthetic Communications, Marcel Dekker, Inc., 27(21):3769-3778 (1997). .
Shohami et al., "Oxidative Stress in Closed-Head Injury: Brain Antioxidant Capacity as an Indicator of Functional Outcome," Journal of Cerebral Blood Flow and Metabolism, Lippincott-Raven Publishers, 17(10):1007-1019 (1997). .
Zurier et al., "Dimethylheptyl-THC-11 OIC Acid," Arthritis & Rheumatism, 41(1):163-170 (1998). .
Hampson et al., "Dual Effects of Anandamide on NMDA Receptor-Mediated Responses and Neurotransmission," Journal of Neurochemistry, Lippincott-Raven Publishers, 70(2):671-676 (1998). .
Hampson et al., "Cannabidiol and (-).DELTA..sup.9 -tetrahydrocannabiono are Neuroprotective Antioxidants," Medical Sciences, Proc. Natl. Acad. Sci. USA, 8268-8273 (1998)..

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