Dr Frankel was recently featured on Paxton Quigley's radio show, "Cannabis Healing", to talk about cannabis and it's use for end of life/palliative care.
This is now the third myasthenia patient who has responded to a combination of CBD, THC and THC-Acid.
This patient was not as critically ill as the last patient so we went a bit slower in adding first CBD –> THC –> THC-Acid. For sure the patient got better as the molecules were added. It seems from just a few patients, that the THC-A is more effective with the small muscles, such as facial and the CBD/THC seem to help the larger muscle groups. Of course many more patients will need to be seen to be more certain of these finer points.
However, it appears that there is no question that CBD/THC/THC-A all help patients with myasthenia.
Possible mechanisms might be that it works like mestanon, the mg drug that increases neuromuscular junction acetylcholine. Another mechanism could be decrease in the patients antibodies against their neuro endplate? My guess is that it increases acetylcholine levels in the neuromuscular junction.
With three out of three patients we have seen very good and promising results. I would love to see more patients.
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