Dr Frankel talks about chemotherapy, it's issues/side effects, and how cannabis can alleviate some of those issues, prevent others, and help enhance the effectiveness of the chemo. He uses a few patient cases to illustrate his approach.
During the past year and a half I have written four articles, both in support of and questioning the use of rectally administered cannabis medicines. As a physician and researcher I’m always looking for new medicines and methods of administration to improve the outcome for my patients. To do so effectively, I must always question and review a medicine’s effectiveness.
I have recommended rectal administration for various conditions, sometimes in conjunction with oral or oral buccal administration. Some of my patients respond well and others do not. Furthermore, to truly establish reasons for such will require a much larger pool of patients.
As I have continued my research and evaluated patient response, I have begun to question rectal administration as an effective method of delivery. My change of opinion is backed by several research studies and discussions with cannabis medicine experts.
Dr Mahmoud ElSohly of NIDA in Mississippi, who’s involved daily in the study of cannabis medicines, makes it clear that years of research in their labs shows that cannabis oil isn’t absorbed rectally. There have been several studies showing oils are not absorbed rectally. Yet, some find better outcomes for patients with certain conditions from rectal administration.
There is anecdotal evidence for both sides of the discussion, some people saying there is psychoactive effect and others who say there is no psychoactive effect.
If high THC cannabis oil gets into the bloodstream, you’ll have a psychoactive effect. If it does not get into the bloodstream, there will be no effect. Many claim they use high THC cannabis without psychoactive effect, and therefore, I’d question if it’s being absorbed.
For my patients receiving benefits from rectal administration, I will continue to recommend they use it. So, patients that don’t benefit from rectally administered cannabis medicines, it’s a natural progression to look to other administration methods.
http://www.sciencedirect.com/science/article/pii/0091305791903534
http://onlinelibrary.wiley.com/doi/10.1002/jps.2600740213/abstract
You Might Also Enjoy...
Dr Frankel talks about chemotherapy, it's issues/side effects, and how cannabis can alleviate some of those issues, prevent others, and help enhance the effectiveness of the chemo. He uses a few patient cases to illustrate his approach.
A recent patient shared their great success in treating their diagnosis of Myasthenia Gravis with cannabis therapies recommended by Dr Frankel
Dr. Mercola interviews Dr. Frankel on many areas of medical cannabis. Topics discussed range from THCV, home growing, dabbing issues, Cannabis Hyperemesis, Myasthenia Gravis and the future of medical cannabis.
Dr Frankel has long been a proponent of using whole plant, cannabis derived CBD products and a recent case in which a patient had less effective results when switching to a prescribed CBD isolate further cemented his stance on what works best for patients
Dr Frankel gives his thoughts and counterpoints on the potential issue of cannabis causing arterial damage after some articles were recently circulating about this subject.
Dr Frankel talks about his experience using THC-V for different medical issues, the initial results he has seen and his hope for more research to be done.