Dr Frankel talks about chemotherapy, it's issues/side effects, and how cannabis can alleviate some of those issues, prevent others, and help enhance the effectiveness of the chemo. He uses a few patient cases to illustrate his approach.
There have been circulating rumors that using THC for treating a hormonally active breast cancer might cause increased estrogen levels and perhaps increase tumor growth. As I looked for data, I came across an article discussing THC and estrogen where it seemed pretty clear that THC decreases estrogen effect. So, with decreasing estrogen effect, THC should actually be helpful in treating hormonally sensitive breast cancers. I would not be concerned about using THC in treating breast cancer and generally use it in a 1:1 ratio with CBD.
In addition, Cannabis smoke has anti-estrogenic effects, decreasing serum estrogen, presumably being helping for treating breast cancer.
So, I cannot find any data showing that THC increases estrogen levels, estrogen binding or estrogen effects.
In summary, THC should decreas estrogen effects and binding and this should have anti-tumor effects for hormonally active breast cancers
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Dr. Mercola interviews Dr. Frankel on many areas of medical cannabis. Topics discussed range from THCV, home growing, dabbing issues, Cannabis Hyperemesis, Myasthenia Gravis and the future of medical cannabis.
Dr Frankel has long been a proponent of using whole plant, cannabis derived CBD products and a recent case in which a patient had less effective results when switching to a prescribed CBD isolate further cemented his stance on what works best for patients