Titration of THC and CBD, or What is Titration

Titration, is the process of slowly increasing one medicine or one liquid, with another medicine, liquid or pretty much anything.

When relating to Cannabinoids, as dosable cannabis medicines are rapidly becoming available, it is becoming more and more important clinically to be able to titrate the cannabinoids. We all have so much to learn in this area, but these are my initial thoughts. I openly encourage comments.

1. For the majority of patients with simple anxiety/insomnia, it is very simple and rarely is any titration necessary. Generally 4 mg or 4 sprays/day is adquate.

2. For the seriously ill or seriously in pain,  just using “pure” whole plant CBD is inadequate; patients require THC. Now comes the titrating. I generally suggest the patient build up a base of CBD, with very little THC. Perhaps somewhere between 10 and 20 mg, we begin adding THC 2 mg (one spray), increased every other day. This seems to minimize the psychoactivity.

It is very clear clinically, at least in my experience, that adding THC to a baseline CBD regimen is a good way to initiate many patient’s programs. The baseline of CBD seems to greatly help the THC side effects.

Allan Frankel, MD Dr Allan Frankel is one of the few physicians in the US who truly understands Cannabis as a medicine. All treatments suggested have been well studied. Every patient seen by Dr Frankel is given a personally created Treatment Plan created with the patient's specific issues defined. Plant medicine requires "tuning" of the dosing. Dr Frankel works with his patients thru a messaging portal. The use of this portal, allows quick and simple follow up contact with Dr Frankel. Patients are not charged for these messages, as this is how Dr Frankel has learned what he has learned. Follow up appointments in person or by phone/video are also available when needed

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